Methylmalonyl Coenzyme A, Free acid

Name: Methylmalonyl Coenzyme A, Free acid
Brand: Coenza

From 580,00 €

CAS No.: 1264-45-5
Synonym(s): Isosuccinyl coenzyme A, Methylmalonyl-CoA

Availability: 6-8 weeks

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Methylmalonyl coenzyme A (Methylmalonyl-CoA) is a substrate used in studying the specificity and kinetics of enzymes like methylmalonyl-CoA mutase, decarboxylase, and hydrolase. It plays a crucial role in the conversion of certain amino acids and odd-chain fatty acids into succinyl-CoA. Methylmalonyl-CoA is essential for understanding metabolic processes, particularly those related to the citric acid cycle (Fenton et al., 2001; Froese et al., 2013).

1. Fenton, W. A., Hack, A. M., Willard, H. F., Gertler, A., Rosenberg, L. E. (2001). Structure and function of methylmalonyl-CoA mutase and methylmalonic aciduria. Progress in Nucleic Acid Research and Molecular Biology, 67, 349–386.

2. Froese, D. S., Kochan, G., Muniz, J. R. C., Wu, X., Gileadi, O., & Gravel, R. A. (2013). Structures of the human GTPase MMAA and vitamin B12-dependent methylmalonyl-CoA mutase and insight into their complex formation. Journal of Biological Chemistry, 288(47), 34066–34076.