Palmitoyl Coenzyme A, Lithium salt

Palmitoyl coenzyme A lithium salt is a crucial molecule involved in palmitoylation, where palmitate is covalently attached to proteins to facilitate membrane binding and regulate cellular signaling, particularly in G-protein pathways. Palmitoyl-CoA lithium salt has been used in various research applications, including microinjection into amphibian oocytes to study citrate synthase inhibition during egg activation, and in assays for thioesterase I activity and S-palmitoylation of cyclophilin D. It plays a key role in the biosynthesis of sphingolipids and is essential for β-oxidation, generating acetyl-CoA for energy production (Nishida et al., 2001; Linder et al., 2021).