Hexanoyl Coenzyme A, Lithium salt
CAS No.: 103476-19-3
Synonym(s): Hexanoyl Coenzyme A, Caproyl Coenzyme A trilithium saltAvailability: 2-3 weeks
Hexanoyl Coenzyme A (Hexanoyl-CoA) is a medium-chain acyl-CoA thioester that functions as a selective acyl donor in both mammalian and plant metabolism. It is utilized by specific enzymes that recognize medium-chain substrates, linking lipid metabolism to the biosynthesis of bioactive molecules. In mammals, Hexanoyl-CoA can be used by ghrelin O-acyltransferase (GOAT) for hormone modification, while in plants it serves as a starter unit for polyketide biosynthesis.¹ ²
Applications
Hexanoyl Coenzyme A is widely used to study enzyme specificity and metabolic pathways.¹ ² In biomedical research, it is important for investigating GOAT activity and developing inhibitors targeting ghrelin signaling in obesity and metabolic disorders.¹ In plant and synthetic biology, it acts as the preferred substrate for olivetol synthase in Cannabis sativa, enabling the production of cannabinoid precursors. Hexanoyl-CoA is also used in metabolic engineering and biocatalysis to generate polyketide libraries and explore medium-chain acyl-CoA utilization.²
Other available forms
